Drug Screening Kits

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Drug Screening Kits to demonstrate how a novel compound affects topoisomerase action from a mechanistic standpoint. Detailed protocols and all necessary controlled reagents are included. Note that enzyme is sold separately.

Topoisomerase I Drug Screening Kit

The Topoisomerase I Drug Screening Kit allows the researcher to model drug action with novel topo I active agents. For example, is it a poison or an inhibitor?

 
Topoisomerase I Drug Screening Kit
$275.00
Topoisomerase I Drug Screening Kit
$375.00

E. coli Topoisomerase IV Drug Screening Kit

The Topoisomerase IV Drug Screeing Kit is designed for researchers who wish to measure the realease of topoisomerase from covalent complexes that form as a result of drug treatment.  It is highly specific and can be quantified.

 
E. coli Topoisomerase IV Drug Screening Kit
$275.00
E. coli Topoisomerase IV Drug Screening Kit
$375.00

Topoisomerase II Drug Screening Kit

The Topoisomerase II Drug Screening Kit will help you interpret how a novel drug affects topo II action.

 
Topoisomerase II Drug Screening Kit
$275.00
Topoisomerase II Drug Screening Kit
$375.00

Topoisomerase II Drug Screening Kit (kDNA based)

This kDNA-based Topo II Drug Kit is designed to idendify agents that target type II topoisomerases acting as catalytic inhibitors, primarily; however, poisons can also be detected. 

 
Topoisomerase II Drug Screening Kit (kDNA based)
$275.00
Topoisomerase II Drug Screening Kit (kDNA based)
$375.00

E. coli DNA Gyrase Drug Screening Kit

DNA Gyrase is an important target for anti-bacterial drugs and new antibiotics are constantly required to deal with drug resistant strains of pathogens. This Kit is designed to identify agents (small molecules, natural products, biological material or synthetics) that directly or indirectly target DNA Gyrase from E. coli.  This Kit includes homogenously purified DNA Gyrase.

E. coli DNA Gyrase Drug Screening Kit
$295.00
E. coli DNA Gyrase Drug Screening Kit
$795.00
E. coli DNA Gyrase Drug Screening Kit
$1,255.00
E. coli DNA Gyrase Drug Screening Kit
$2,255.00

Topoisomerase I Hi-Loading Inhibition Kit

This kit is designed to allow the customer to screen for agents (drugs, natural products, small molecules, synthetics) that block the catalytic activity of human topoisomerase I (topo I).

 
Topoisomerase I Hi-Loading Inhibition Kit
$325.00
Topoisomerase I Hi-Loading Inhibition Kit
$395.00