The Topoisomerase I Drug Screening Kit allows the researcher to model drug action with novel topo I active agents. For example, is it a poison or an inhibitor?
The Topoisomerase IV Drug Screeing Kit is designed for researchers who wish to measure the realease of topoisomerase from covalent complexes that form as a result of drug treatment. It is highly specific and can be quantified.
The Topoisomerase II Drug Screening Kit will help you interpret how a novel drug affects topo II action.
This kDNA-based Topo II Drug Kit is designed to idendify agents that target type II topoisomerases acting as catalytic inhibitors, primarily; however, poisons can also be detected.
DNA Gyrase is an important target for anti-bacterial drugs and new antibiotics are constantly required to deal with drug resistant strains of pathogens. This Kit is designed to identify agents (small molecules, natural products, biological material or synthetics) that directly or indirectly target DNA Gyrase from E. coli. This Kit includes homogenously purified DNA Gyrase.
This kit is designed to allow the customer to screen for agents (drugs, natural products, small molecules, synthetics) that block the catalytic activity of human topoisomerase I (topo I).