About

TopoGEN, Inc. provides innovative reagents and kits for topoisomerase research and mechanism-based drug development. Kits are available to assay for topoisomerases (I, II, IV and gyrase) and Tdp1, to assay for topo inhibition in cells and to characterize topoisomerase inhibitors. DNA substrates, topo inhibitors, antibodies, and kit replacement reagents are also available. Products are listed in our on-line catalog; for descriptions of recent additions, see new reagents. If you are interested in details of our recent lots of products, Frequently asked questions, Technical literature and brochures, see Technical Information.
If you would like to immediately place an order go to our secure location here.

Go to the following pages for specific products:

Topo Related Antibodies/Immunochemicals: Check our new trial sizes!

Why buy DNA, Enzymes and AB from TopoGEN?

Topo enzymes are sensitive to DNA quality (for example, heavy metal contamination) and not all DNA preps will support activity.
All of our DNA products are screened to support Topoisomerase (and gyrase) activity.
We offer competitive prices on our products.
We can provide scientific input from research experts who have extensive knowledge and experience in the topo field.
Our staff offers excellent support for product applications
We know what works and what does not work... we can help transfer complex technology to your staff with minimal down time.

Don’t waste expensive enzymes on inferior DNA substrate...do it right and get the best!.

We offer custom screening on a contract basis. Let us test your compounds for topo targeting activity.