Decatenated Kinetoplast DNA (KDNA): A marker for Topo II Assays
TopoGEN supplies you with a decatenated form of KDNA for use as a marker with the topo II assay kit. Highly purified topo II is used to release the minicircles which show up as two bands: Nicked 2.5 kb DNA rings and relaxed (circular) 2.5 kb KDNA minicircles. The ratios between these two forms varies but usually the nicked species is more prevalent.

We offer custom screening on a contract basis. Let us test your compounds for topo targeting activity. ![]()
Technical Questions?
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TopoGEN, Inc.
108 Aces Alley
Port Orange, FL, USA 32128
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Updated December 26, 2006