614-451-5810 
Inhibitors and Poisons
Catalytic inhibitors and poisons that induce cleavage. For use in TopoGEN kits.
- Topotecan Hydrochloride (Hycamtin)
- Irinotecan (CPT-11)
- 9-Nitro-20 (S) Camptothecin (Rubitecan)
- 10-Hydroxy Camptothecin
- 9-Amino Camptothecin
- Camptothecin
- Doxorubicin (Adriacin)
- Daunomycin
- Etoposide (VP16)
- Ellipticine
- Ciproflaxin
- Amsacrine (m-AMSA)
- Genistein
Topotecan Hydrochloride (Hycamtin)
Topotecan is a semi-synthetic derivative of camptothecin and anti-tumor drug that targets topo I. As a topo I poison it induces cleavage complexes.
| SKU | Product | Size | Price | Buy |
|---|---|---|---|---|
| TG4100 | Topotecan Hydrochloride (Hycamtin) | 0.25 ml | $199.00 |  |
Irinotecan (CPT-11)
Water soluble, semi-synthetic analogue of 20(S) camptothecin (CPT) with promising activity against a range of tumor types.
| SKU | Product | Size | Price | Buy |
|---|---|---|---|---|
| TG4101 | Irinotecan (CPT-11) | 0.25 ml | $109.00 | |
9-Nitro-20 (S) Camptothecin (Rubitecan)
Rubitecan (9-nitro-CPT) is a control poison/inhibitor of topo I with promising activity against a range of tumor types.
| SKU | Product | Size | Price | Buy |
|---|---|---|---|---|
| TG4102 | 9-Nitro-20 (S) Camptothecin (Rubitecan) | 0.25ml | $109.00 | |
10-Hydroxy Camptothecin
A control poison/inhibitor of topo I with promising activity against a range of tumor types.
| SKU | Product | Size | Price | Buy |
|---|---|---|---|---|
| TG4103 | 10-Hydroxy Camptothecin | 0.25 ml | $109.00 | |
9-Amino Camptothecin
This is an analog of camptothecin showing promising activity against a range of tumor types. It is provided as a control poison/inhibitor of topo I.
| SKU | Product | Size | Price | Buy |
|---|---|---|---|---|
| TG4104 | 9-Amino Camptothecin | 0.25 ml | $109.00 | |
Camptothecin
This topo I poison both inhibits enzyme activity and stabilizes formation of topo I cleavage complexes.
| SKU | Product | Size | Price | Buy |
|---|---|---|---|---|
| TG4110 | Camptothecin | Lyophilized | $99.00 | |
Doxorubicin (Adriacin)
Doxorubicin (Adriacin) is a control poison/inhibitor of topo II.
| SKU | Product | Size | Price | Buy |
|---|---|---|---|---|
| TG4120 | Doxorubicin (Adriacin) | 0.25 ml | $109.00 | |
Daunomycin
This is a control poison/inhibitor of topo II.
| SKU | Product | Size | Price | Buy |
|---|---|---|---|---|
| TG4130 | Daunomycin | 0.25 ml | $99.00 | |
Etoposide (VP16)
This is a control poison/inhibitor of topo II. It is also included in the topo II drug screening kit.
| SKU | Product | Size | Price | Buy |
|---|---|---|---|---|
| TG4140 | Etoposide (VP16) | Lyophilized | $99.00 | |
Ellipticine
Ellipticine is a topo II poison that induces topo II dependent cleavages.
| SKU | Product | Size | Price | Buy |
|---|---|---|---|---|
| TG4170 | Ellipticine | 0.25 ml | $99.00 | |
Ciproflaxin
A control poison/inhibitor of DNA Gyrase and Topo IV. This is also included in the Topo IV/Gyrase Drug Screening Kits.
| SKU | Product | Size | Price | Buy |
|---|---|---|---|---|
| TG4180 | Ciproflaxin | 50 ul | $69.00 | |
Amsacrine (m-AMSA)
This is a control poison/inhibitor of topoisomerase II.
| SKU | Product | Size | Price | Buy |
|---|---|---|---|---|
| TG4150 | Amsacrine (m-AMSA) | 0.25 ml | $99.00 | |
Genistein
Isoflavone and inhibitor of tyrosine protein kinases reported to induce topo II dependent cleavages.
| SKU | Product | Size | Price | Buy |
|---|---|---|---|---|
| TG4160 | Genistein | 0.25 ml | $99.00 | |