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The Topoisomerase I in vivo Link Kit offers a very powerful method to deduce whether a given drug actually affects its predicted topo target in a given cancer cell in vivo. One can quantify the activity of topoisomerase enzyme in vivo with this kit.
Whether you are conducting your first topo I specific assay or you have multiple publications identifying novel topoisomerase inhibitors, you are aware that working with catalytically active proteins can involve extra time constra...
The authors discuss the particulars of the perinucluear compartment in DNA and its effects on the DNA integrity of a tumor rich environment. Human Topo I Antibody provided by TopoGEN. Article Source: The Journal of Biologica...
TopoGEN is a research diagnostic company that provides innovative products for researchers working with topoisomerases and engaged in mechanism based drug discovery. Kits are available to identify topoisomerase active drugs for use in cancer chemotherapy and antibacterial applications. The company also provides kits for assaying both prokaryotic and eukaryotic topoisomerases (type I, II, IV, gyrase), both in vitro and in vivo.
We also offer a complete line of DNA substrates and DNA cleavage targets, topo inhibitors, antibodies, and kit replenishment reagents. The company was founded by researchers working