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Topoisomerase Assay Kits
Detailed protocols and controlled reagents for topoisomerase kits and related products. Note that enzyme is sold separately, except where otherwise indicated.
- Gyrase Assay Kit
- Human Topoisomerase II Assay Kit
- Topoisomerase I Assay Kit
- SDS-K+ Precipitation Kit (in vivo)
- Topoisomerase I In Vivo Link Kit
- Topoisomerase II In Vivo Link Kit
- SDS-K+ Precipitation Kit (in vitro)
- DNA Intercalator/Unwinding Kit
- Gyrase/Relaxed DNA Assay Kit
Gyrase Assay Kit
The DNA Gyrase Assay Kit will allow one to quantify gyrase activity in a crude mix of other proteins (other topoisomerase enzymes for example). It is ideal for characterizing inhibitors as well.
| SKU | Product | Size | Price | Buy |
|---|---|---|---|---|
| TG1003 | Gyrase Assay Kit | 100 Assays | $299.00 |  |
Human Topoisomerase II Assay Kit
The Human Topoisomerase II Assay Kit is designed for researchers who wish to measure topo II activity in a crude extract. It is highly specific and can be quantified.
| SKU | Product | Size | Price | Buy |
|---|---|---|---|---|
| TG1001-1 | Human Topoisomerase II Assay Kit | 100 Assays | $269.00 | |
| TG1001-2 | Human Topoisomerase II Assay Kit | 250 Assays | $379.00 | |
Topoisomerase I Assay Kit
The Topoiosomerase I Assay Kit is a specific assay for topo I in a crude mixture of heterologous proteins. It is generally easy to interpret an assay that quantifies topo I activity.
| SKU | Product | Size | Price | Buy |
|---|---|---|---|---|
| TG1015-1 | Topoisomerase I Assay Kit | 100 Assays | $249.00 | |
| TG1015-2 | Topoisomerase I Assay Kit | 250 Assays | $349.00 | |
SDS-K+ Precipitation Kit (in vivo)
Designed for researchers who wish to monitor topoisomerase I or II covalent binding to a DNA target in vitro AND in vivo.
| SKU | Product | Size | Price | Buy |
|---|---|---|---|---|
| TG1011-1 | SDS-K+ Precipitation Kit (in vivo) | 100 Assays | $299.00 | |
| TG1011-2 | SDS-K+ Precipitation Kit (in vivo) | 250 Assays | $379.00 | |
Topoisomerase I In Vivo Link Kit
The Topoisomerase I in vivo Link Kit offers a very powerful method to deduce whether a given drug actually affects its predicted topo target in a given cancer cell in vivo. One can quantify the activity of topoisomerase enzyme in vivo with this kit.
| SKU | Product | Size | Price | Buy |
|---|---|---|---|---|
| TG1021 | Topoisomerase I In Vivo Link Kit | 200 Assays | $399.00 | |
Topoisomerase II In Vivo Link Kit
The Topoisomerase II in vivo Link Kit provides a very powerful method to deduce whether a given drug actually affects its predicted topo target in a given cancer cell in vivo. One can quantify the activity of topoisomerase in vivo with this kit.
| SKU | Product | Size | Price | Buy |
|---|---|---|---|---|
| TG1022 | Topoisomerase II In Vivo Link Kit | 200 Assays | $469.00 | |
SDS-K+ Precipitation Kit (in vitro)
Designed for researchers who wish to monitor topoisomerase I or II covalent binding to a DNA target in vitro AND in vivo.
| SKU | Product | Size | Price | Buy |
|---|---|---|---|---|
| TG1010-1 | SDS-K+ Precipitation Kit (in vitro) | 100 Assays | $299.00 | |
| TG1010-2 | SDS-K+ Precipitation Kit (in vitro) | 250 Assays | $399.00 | |
DNA Intercalator/Unwinding Kit
The DNA Intercalator/Unwinding Kit wil reveal how a particular drug intercalates and unwinds the DNA helix.
| SKU | Product | Size | Price | Buy |
|---|---|---|---|---|
| TG1025 | DNA Intercalator/Unwinding Kit | 50 Experiments | $349.00 | |
Gyrase/Relaxed DNA Assay Kit
TopoGEN sells E. coli gyrase along with the relaxed DNA subtrate. The enzyme is very active and can be purchased in large quantities for screening studies.
| SKU | Product | Size | Price | Buy |
|---|---|---|---|---|
| TG2000G-1KIT | Gyrase/Relaxed DNA Assay Kit | 100 Assays | $469.00 | |
| TG2000G-3KIT | Gyrase/Relaxed DNA Assay Kit | 500 Assays | $899.00 | |
| TG2000G-5KIT | Gyrase/Relaxed DNA Assay Kit | 1000 Assays | $1,399.00 | |
| TG2000G-7KIT | Gyrase/Relaxed DNA Assay Kit | 2000 Assays | $1,999.00 | |