TopoGEN Topoisomerase Antibodies Used in Chemotherapy Study
Topoisomerase levels determine chemotherapy response in vitro and in vivo Darren J. Burgess*, Jason Doles†, Lars Zender*, Wen Xue*, Beicong Ma*‡, W. Richard McCombie*, Gregory J. Hannon*‡, Scott W. Lowe*‡§, and Michael T. Hemann*† *Cold Spring Harbor Laboratory and ‡Howard Hughes Medical Institute, 1 Bungtown Road, Cold Spring Harbor, NY 11724; and †Center for Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139 Communicated by Michael H. Wigler, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, April 14, 2008 (received…