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Month: September 2014

Topoisomerase II Drug Screening and Xanthocidin

Topoisomerase II Drug Screening and Xanthocidin

These researchers have cleverly identified a way to synthesize derivatives of an unstable compound group with potential as Topoisomerase IIa inhibitors. Topo II and Drug Screening kits for the analysis of enzyme reactivity and DNA cleavage were provided by TopoGEN. Article Source: The Pharmaceutical Society of Japan Biological and Pharmaceutical Bulletin Xanthocidin Derivatives as Topoisomerase II╬▒ Enzymatic Inhibitors Abstract Few studies have examined xanthocidin, a biotic isolated from Streptomyces xanthocidicus in 1966, because its supply is limited. Based on its…

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