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Novel Targeting In Vivo based on DNA DS Breaks and Homologous Recombination

Novel Targeting In Vivo based on DNA DS Breaks and Homologous Recombination

TopoGEN scientists are working on a novel screening kit that reports on the topo II mediated DNA damage.  The kit comes bundled with a HR repair reporter that TopoGEN scientist engineered using GFP inside cells that contain an ultra-high affinity site for topoisomerase II cleavages.  The quantitative GFP readout will allow in vivo screening for topo active and DNA damaging agents.  This kit is slated for release in 2012, so please contact us for more information.

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