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Tag: Human Topoisomerase I

SBIR-Funded Alliance to Conquer the Cold-Chain

SBIR-Funded Alliance to Conquer the Cold-Chain

Recently, TopoGEN was featured in the local press in order to showcase our collaboration with Nanoly Bioscience based out of Boulder.  Nanoly has developed a polymer-based cage (the NanoShield) that can protect labile products from fluctuations in temperature and possibly obviate need for expensive dry ice transit around the world.  TopoGEN is going to field test the NanoShield with our Human Topo I and garner end-user feedback via our extensive distribution network in Europe and Asia.  This venture is being…

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Topo I Assay Quickstart: How to get the assay properly validated and established in my lab?

Topo I Assay Quickstart: How to get the assay properly validated and established in my lab?

Whether you are conducting your first topo I specific assay or you have multiple publications identifying novel topoisomerase inhibitors, you are aware that working with catalytically active proteins can involve extra time constraints if you do not first validate the working conditions of your assay. The following simple experiment should be performed when you receive your human topoisomerase I enzyme and topoisomerase I assay kit. You must show that in your lab, you can detect topo activity. This experiment is…

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