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Tag: Topoisomerases and Enzymatic Activity

SBIR-Funded Alliance to Conquer the Cold-Chain

SBIR-Funded Alliance to Conquer the Cold-Chain

Recently, TopoGEN was featured in the local press in order to showcase our collaboration with Nanoly Bioscience based out of Boulder.  Nanoly has developed a polymer-based cage (the NanoShield) that can protect labile products from fluctuations in temperature and possibly obviate need for expensive dry ice transit around the world.  TopoGEN is going to field test the NanoShield with our Human Topo I and garner end-user feedback via our extensive distribution network in Europe and Asia.  This venture is being…

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Topoisomerases and Enzymatic Activity: A How-To Guide to Establishing Activity

Topoisomerases and Enzymatic Activity: A How-To Guide to Establishing Activity

If you experience low or no activity with our enzymes, consider doing a ‘reconstruction’ type of experiment as follows. Note that this is generally good practice upon receipt of new enzyme from TopoGEN, just to verify that everything is working properly in your lab. FIRST, When you receive your product, be sure to store as directed by the product literature. Often this means placing immediately at -70ºC. In some cases you can thaw and aliquot the enzyme (not less than…

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