DNA Substrates & Markers
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DNA Substrates & Markers
Kinetoplast DNA (kDNA)
kDNA is the ideal substrate for topoisomerase II assays because it is specific for type II reaction mechanisms. Researchers can even assay for a type II enzyme in the presence of large excess of topoisomerase I.
pRYG DNA
pRYG DNA is a supercoiled plasmid containing multiple clusters of topoisomerase II cleavage sites.
Supercoiled pHOT-1 DNA
Supercoiled pHOT-1 DNA is a perfect substrate for assaying any topoisomerase. Specifically, the plasmid is relatively small (<3KB) which is ideal for displaying intermediate topoisomers.
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New Cell Based Screening Systems for NHEJ and HR Now Available
This short video describes our new Cell Based Screening Systems for DNA Repair. Mouse and human cell line kits are available, and we can custom engineer our reporters into any mammalian cell line you provide. [video ...
This short video describes our new Cell Based Screening Systems for DNA Repair. Mouse and human cell line kits are available, and we can custom engineer our reporters into any mammalian cell line you provide. [video ...
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New Cell Based Screening Systems for NHEJ and HR Now Available
This short video describes our new Cell Based Screening Systems for DNA Repair. Mouse and human cell line kits are available, and we can custom engineer our reporters into any mammalian cell line you provide. [video ...
This short video describes our new Cell Based Screening Systems for DNA Repair. Mouse and human cell line kits are available, and we can custom engineer our reporters into any mammalian cell line you provide. [video ...
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