DNA Substrates & Markers
Home > Dna-substrates-markers
DNA Substrates & Markers
Kinetoplast DNA (kDNA)
kDNA is the ideal substrate for topoisomerase II assays because it is specific for type II reaction mechanisms. Researchers can even assay for a type II enzyme in the presence of large excess of topoisomerase I.
Supercoiled pHOT-1 DNA
Supercoiled pHOT-1 DNA is a perfect substrate for assaying any topoisomerase. Specifically, the plasmid is relatively small (<3KB) which is ideal for displaying intermediate topoisomers.
Relaxed pHOT-1 DNA
Relaxed pHOT-1 DNA - ideal for assaying the supercoiling activity of DNA Gyrase.
-
TopoGEN, Inc.
27960 County Rd. 319
Hangar B
Buena Vista, CO 81211
USA - 614-451-5810
- 614-559-3932
- Mon-Fri: 8AM to 5PM
Closed Saturday and Sunday 
Useful Links
Latest News
Latest Google Scholar Results
Complete listing of the latest Google Scholar results that reference the use of TopoGEN Products....
Complete listing of the latest Google Scholar results that reference the use of TopoGEN Products....
Latest Blogs
Quantifying Topo Action in E. Coli
A new method to quantify endogenous Topoisomerase action in E. coli cells is nicely described in this paper. The technique is based on the In Vivo Link Kit, also known as the ICE bioassay. Article Source: American Society for Mi...
A new method to quantify endogenous Topoisomerase action in E. coli cells is nicely described in this paper. The technique is based on the In Vivo Link Kit, also known as the ICE bioassay. Article Source: American Society for Mi...
© Copyright 2018 TopoGEN, Inc.