DNA Substrates & Markers
Home > Dna-substrates-markers
DNA Substrates & Markers
Kinetoplast DNA (kDNA)
kDNA is the ideal substrate for topoisomerase II assays because it is specific for type II reaction mechanisms. Researchers can even assay for a type II enzyme in the presence of large excess of topoisomerase I.
Supercoiled pHOT-1 DNA
Supercoiled pHOT-1 DNA is a perfect substrate for assaying any topoisomerase. Specifically, the plasmid is relatively small (<3KB) which is ideal for displaying intermediate topoisomers.
Relaxed pHOT-1 DNA
Relaxed pHOT-1 DNA - ideal for assaying the supercoiling activity of DNA Gyrase.
-
TopoGEN, Inc.
27960 County Rd. 319
Hangar B
Buena Vista, CO 81211
USA - 614-451-5810
- 614-559-3932
- Mon-Fri: 8AM to 5PM
Closed Saturday and Sunday 
Useful Links
Latest News
Latest Google Scholar Results
Complete listing of the latest Google Scholar results that reference the use of TopoGEN Products....
Complete listing of the latest Google Scholar results that reference the use of TopoGEN Products....
Latest Blogs
Nuclease Assays with pN01 from TopoGEN
Saccharomyces cerevisiae Mre11/Rad50/Xrs2 and Ku proteins regulate association of Exo1 and Dna2 with DNA breaks Eun Yong Shim1,4, Woo-Hyun Chung2,4, Matthew L Nicolette3, Yu Zhang1, Melody Davis1, Zhu Zhu2, Tanya T Paull3, Grze...
Saccharomyces cerevisiae Mre11/Rad50/Xrs2 and Ku proteins regulate association of Exo1 and Dna2 with DNA breaks Eun Yong Shim1,4, Woo-Hyun Chung2,4, Matthew L Nicolette3, Yu Zhang1, Melody Davis1, Zhu Zhu2, Tanya T Paull3, Grze...
© Copyright 2019 TopoGEN, Inc.