DNA Substrates & Markers

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DNA Substrates & Markers

Kinetoplast DNA (kDNA)

kDNA is the ideal substrate for topoisomerase II assays because it is specific for type II reaction mechanisms.  Researchers can even assay for a type II enzyme in the presence of large excess of topoisomerase I.  

Kinetoplast DNA (kDNA)
$145.00
Kinetoplast DNA (kDNA)
$225.00
Kinetoplast DNA (kDNA)
$675.00

Linear kDNA

Linear Kinetoplast DNA Marker

 
Linear kDNA
$95.00

pRYG DNA

pRYG DNA is a supercoiled plasmid containing multiple clusters of topoisomerase II cleavage sites.

 
pRYG DNA
$195.00

Supercoiled pHOT-1 DNA

Supercoiled pHOT-1 DNA is a perfect substrate for assaying any topoisomerase.  Specifically, the plasmid is relatively small (<3KB) which is ideal for displaying intermediate topoisomers.

Supercoiled pHOT-1 DNA
$95.00
Supercoiled pHOT-1 DNA
$125.00
Supercoiled pHOT-1 DNA
$455.00

Supercoiled pBR322 DNA

Supercoiled pBR322 DNA is suited for assaying any topoisomerase.

 
Supercoiled pBR322 DNA
$229.00
Supercoiled pBR322 DNA
$559.00

Relaxed pBR322 DNA

Relaxed pBR322 DNA - suited for assaying supercoiling by DNA gyrase.

 
Relaxed pBR322 DNA
$249.00
Relaxed pBR322 DNA
$599.00

Decatenated kDNA

Decatenated Kinetoplast DNA Marker

 
Decatenated kDNA
$95.00

Relaxed pRYG DNA Marker

Relaxed pRYG DNA Marker

 
Relaxed pRYG DNA Marker
$175.00

Linear pRYG DNA Marker

Linear pRYG DNA Marker

 
Linear pRYG DNA Marker
$95.00

Relaxed pHOT-1 DNA

Relaxed pHOT-1 DNA - ideal for assaying the supercoiling activity of DNA Gyrase. 

Relaxed pHOT-1 DNA
$105.00
Relaxed pHOT-1 DNA
$135.00
Relaxed pHOT-1 DNA
$475.00