DNA Substrates & Markers
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DNA Substrates & Markers
Kinetoplast DNA (kDNA)
kDNA is the ideal substrate for topoisomerase II assays because it is specific for type II reaction mechanisms. Researchers can even assay for a type II enzyme in the presence of large excess of topoisomerase I.
Supercoiled pHOT-1 DNA
Supercoiled pHOT-1 DNA is a perfect substrate for assaying any topoisomerase. Specifically, the plasmid is relatively small (<3KB) which is ideal for displaying intermediate topoisomers.
Relaxed pHOT-1 DNA
Relaxed pHOT-1 DNA - ideal for assaying the supercoiling activity of DNA Gyrase.
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Complete listing of the latest Google Scholar results that reference the use of TopoGEN Products....
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New Findings about RNA Topoisomerase in Animal Species
In an exciting new paper by Ahmad et al (1), a new RNA topoisomerase function as been ascribed to several pro and eukaryotic DNA topoisomerase activities. While others have evidence for such interesting and novel activity on an R...
In an exciting new paper by Ahmad et al (1), a new RNA topoisomerase function as been ascribed to several pro and eukaryotic DNA topoisomerase activities. While others have evidence for such interesting and novel activity on an R...
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