Tdp2 Substrate

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Tdp2 Substrate

Tyrosyl DNA Phosphodiesterase 2 (TDP-2) Substrate

TDP-2 is specifically directed to act on phosphotyrosyl bonds that form when topoisomerase II is covalently trapped on the DNA helix. We now offer the actual DNA substrate for Tdp2.  This substrate is a native Top2/DNA covalent complex that is acted on by Tdp2 and releases free DNA.  The assay is rapidly and easily performed using a simple agarose gel electrophoretic separation.

 
Tyrosyl DNA Phosphodiesterase 2 (TDP-2) Substrate
$295.00
Tyrosyl DNA Phosphodiesterase 2 (TDP-2) Substrate
$395.00