Topo I
Topotecan Hydrochloride (Hycamtin)
Topotecan is a semi-synthetic derivative of camptothecin and anti-tumor drug that targets topo I. As a topo I poison it induces cleavage complexes.
Irinotecan (CPT-11)
Irinotecan (CPT-11) is a water soluble, semi-synthetic analogue of 20(S) camptothecin (CPT) with promising activity against a range of tumor types.
9-Nitro-20 (S) Camptothecin (Rubitecan)
Rubitecan (9-nitro-CPT) is a control poison/inhibitor of topo I with promising activity against a range of tumor types.
10-Hydroxy Camptothecin
10-Hydroxy Camptothecin is a control poison/inhibitor of topo I with promising activity against a range of tumor types.
9-Amino Camptothecin
9-Amino Camptothecin is an analog of camptothecin showing promising activity against a range of tumor types. It is provided as a control poison/inhibitor of topo I.
Camptothecin
Camptothecin is a topo I poison that both inhibits enzyme activity and stabilizes formation of topo I cleavage complexes.
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TopoGEN, Inc.
27960 County Rd. 319
Hangar B
Buena Vista, CO 81211
USA - 614-451-5810
- 614-559-3932
- Mon-Fri: 8AM to 5PM
Closed Saturday and Sunday 
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Immunization with DNA topoisomerase I and Freund's complete adjuvant induces skin and lung fibrosis and autoimmunity via interleukin-6 signaling. Abstract OBJECTIVE: The presence of anti-DNA topoisomerase I (anti-topo I) anti...