Topo Related Drugs

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Topo Related Drugs

Topotecan Hydrochloride (Hycamtin)

Topotecan is a semi-synthetic derivative of camptothecin and anti-tumor drug that targets topo I.  As a topo I poison it induces cleavage complexes.

 
Topotecan Hydrochloride (Hycamtin)
$85.00

Irinotecan (CPT-11)

Irinotecan (CPT-11) is a water soluble, semi-synthetic analogue of 20(S) camptothecin (CPT) with promising activity against a range of tumor types.

 
Irinotecan (CPT-11)
$85.00

9-Nitro-20 (S) Camptothecin (Rubitecan)

Rubitecan (9-nitro-CPT) is a control poison/inhibitor of topo I with promising activity against a range of tumor types.

 
9-Nitro-20 (S) Camptothecin (Rubitecan)
$85.00

10-Hydroxy Camptothecin

10-Hydroxy Camptothecin is a control poison/inhibitor of topo I with promising activity against a range of tumor types.

 
10-Hydroxy Camptothecin
$85.00

9-Amino Camptothecin

9-Amino Camptothecin is an analog of camptothecin showing promising activity against a range of tumor types.  It is provided as a control poison/inhibitor of topo I.

 
9-Amino Camptothecin
$85.00

Camptothecin

Camptothecin is a topo I poison that both inhibits enzyme activity and stabilizes formation of topo I cleavage complexes.

 
Camptothecin
$85.00

Doxorubicin (Adriacin)

Doxorubicin (Adriacin) is a control poison/inhibitor of topoisomerase II. 

 
Doxorubicin (Adriacin)
$85.00

Daunomycin

Daunomycin is a control poison/inhibitor of topo II.

 
Daunomycin
$85.00

Etoposide (VP16)

Etoposide  (VP16) is a control poison/inhibitor of topo II.  It is also included in the topo II drug screening kit.

 
Etoposide (VP16)
$85.00

Ellipticine

Ellipticine is a topo II poison that induces topo II dependent cleavages. 

 
Ellipticine
$85.00

Ciprofloxacin

Ciproflaxin is a control poison/inhibitor of DNA Gyrase and Topo IV.  This is also included in the Topo IV Drug Screening Kit

 
Ciprofloxacin
$85.00

Amsacrine (m-AMSA)

Amsacrine (m-AMSA) is a control poison/inhibitor of topoisomerase II.

 
Amsacrine (m-AMSA)
$85.00

Genistein

Genistein is an isoflavone and inhibitor of tyrosine protein kinases reported to induce topo II dependent cleavages.

 
Genistein
$85.00

HU-331

HU-331 is a cannabinoid-based quinone with potential anticancer activity.  It has anti-topo IIa activity as a catalytic inhibitor rather than a poison. 

 
HU-331
$85.00