Topoisomerase Assay Kits

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Detailed protocols and controlled reagents for topoisomerase kits and related products. Note that enzyme is sold separately, except where otherwise indicated.

Topoisomerase I Assay Kit

The Topoiosomerase I Assay Kit is a specific assay for topo I in a crude mixture of heterologous proteins. It is generally easy to interpret an assay that quantifies topo I activity.

 
Topoisomerase I Assay Kit
$195.00
Topoisomerase I Assay Kit
$295.00

Gyrase Assay Kit

The DNA Gyrase Assay Kit will allow one to quantify gyrase activity in a crude mix of other proteins (other topoisomerase enzymes for example). It is ideal for characterizing inhibitors as well.

 
Gyrase Assay Kit
$195.00

Human Topoisomerase II Assay Kit

The  Human Topoisomerase II Assay Kit is designed for researchers who wish to measure topo II activity in a crude extract. It is highly specific and can be quantified.

 
Human Topoisomerase II Assay Kit
$195.00
Human Topoisomerase II Assay Kit
$295.00

SDS-K+ Precipitation Kit (in vivo)

Designed for researchers who wish to monitor topoisomerase I or II covalent binding to a DNA target in vitro AND in vivo.

 
SDS-K+ Precipitation Kit (in vivo)
$195.00
SDS-K+ Precipitation Kit (in vivo)
$295.00

SDS-K+ Precipitation Kit (in vitro)

Designed for researchers who wish to monitor topoisomerase I or II covalent binding to a DNA target in vitro AND in vivo. 

 
SDS-K+ Precipitation Kit (in vitro)
$315.00
SDS-K+ Precipitation Kit (in vitro)
$415.00

DNA Intercalator/Unwinding Kit

The DNA Intercalator/Unwinding Kit wil reveal how a particular drug intercalates and unwinds the DNA helix.  

 
DNA Intercalator/Unwinding Kit
$395.00
  • SKU TG1025
  • Size
  • 50 Experiments

E. coli DNA Gyrase and Relaxed DNA Assay Kit

TopoGEN sells E. coli DNA gyrase along with the relaxed DNA subtrate (pHOT-1).  The enzyme is very active and can be purchased in large quantities for screening studies.

E. coli DNA Gyrase and Relaxed DNA Assay Kit
$235.00
E. coli DNA Gyrase and Relaxed DNA Assay Kit
$755.00
E. coli DNA Gyrase and Relaxed DNA Assay Kit
$1,195.00
E. coli DNA Gyrase and Relaxed DNA Assay Kit
$2,195.00

TopII-NucEx Kit

Prepare a nuclear extract enriched for type II topoisomerase (topo II) activity and topo II polypeptide. 

 
TopII-NucEx Kit
$275.00

TopI-NucEx Kit

Prepare a nuclear extract enriched for type I topoisomerase (topo I) activity and intact 100 kDa polypeptide.

 
TopI-NucEx Kit
$265.00